- The Daeva evoke the image of vampires as seductive, decadent, sexually transgressive predators who blur lust and hunger together, equating the act of feeding with sensual pleasure. The majority of "Succubi" are found within the Invictus.
- The Gangrel embody the idea of vampires as predatory feral demons. The "Savages" are often devoted to the Circle of the Crone, though more 'pro-active' Kindred align with the Carthian Movement.
- The Mekhet embody the idea of a shadowy vampire lord, omniscient and unseen. The "Shadows" are frequently found with the Carthian Movement or Lancea et Santumn, though a number also work within the Circle of the Crone.
- The Nosferatu are the repulsive, yet fascinating, alien monsters of legend. The 'Haunts' can be found within every Covenant.
- The Ventrue are regal vampires who value power and dominion to the point of obsession, self-styled "lords of the night". These "Lords" are often associated with the Invictus, though just as many work within the Ordo Dracul.
Exceptions exist, but are few and far between. The Akhud were tied to an ancient Middle-Eastern curse, if they existed at all. The Julii vanished with Rome, apparently destroyed by the Strix. The strange Pijavica of Eastern Europe were gone by the end of the 19th century. And the Jiang Shi are kept in a Malthusian check of their own awkward Embrace.
Certain clan members find ways to refine their Blood, transmuting it such they develop new powers and flaws, though they retain quintessential qualities of their clan. Such lineages are known as Bloodlines. Most bloodlines can only exist within certain clans, though rare exceptions of multi-clan bloodlines do exist.